科研项目
国家自然科学基金委青年基金，五味子木脂素组分抑制认知相关脑区中小胶质细胞M1型极化治疗阿尔茨海默病的药效物质及机制研究，负责人（2023-2025）
论文与专利
1. Yuying Wu#, Mengying Wei#, Mengyao Wang, Minsong Guo, Hengyuan Yu, Yong Chen, Tengfei Xu,Yuan Zhou*, Schisandra total lignans ameliorate neuronal ferroptosis in 3xTg-AD mice via regulating NADK/NADPH/GSH pathway. Phytomedicine, 2025, 140:156612.
2. Zhao Jiahui#; Wei Mengying#;Guo Minsong; Wang Mengyao; Niu Hongxia; Xu Tengfei; Zhou Yuan*; GSK3: A potential target and pending issues for treatment of Alzheimer's disease, CNS Neuroscience & Therapeutics, 2024, 30(7): e14818.
3. Wei Mengying; Liu Zhongying*; Liu Yuanyuan; Li Shizhe; Hu Mingxin; Yue Kexin; Liu Tianshu; He Yang; Pi Zifeng*; Liu Zhiqiang; Song Fengrui; Urinary and plasmatic metabolomics strategy to explore the holistic mechanism of lignans in S. chinensis in treating Alzheimer's disease using UPLC-Q-TOF-MS, Food & Function, 2019, 10(9): 5656-5668.
4. Hong Huang, Chuanming Fang, Hongxia Niu, Xiangjun Yin, Jiazhao Ruan, Mengying Wei*,
Yuan Zhou *; Effects of donepezil treatment on plasma and urine metabolites in amyloid beta-induced Alzheimer’s disease rats, Journal of Chromatography B, 2023, 1224: 123766.
5. Zhou Yuan（共一）; Wei Mengying（共一）; Fan Meiling; Liu Zhongying*; Wang Aimin; Liu Yuanyuan; Men Lihui; Pi Zifeng*; Liu Zhiqiang; Song Fengrui; Pharmacokinetic and metabolomics approach based on UHPLC-MS to evaluate therapeutic effect of lignans from S. Chinensis in alzheimer's disease, Journal of Chromatography B, 2021, 1178: 122859.
6. Wei Mengying; Ma Yinghui; Liu Yuanyuan; Zhou Yuan; Men Lihui; YueK exin; Pi Zifeng; Liu Zhiqiang; Liu Zhongying*; Urinary metabolomics study on the anti-inflammation effects of flavonoids obtained from Glycyrrhiza, Journal of Chromatography B, 2018, 1086(1086): 1-10.
7. Wei Mengying; Liu Yuanyuan; Pi Zifeng; Yue Kexin; Li Shizhe; Hu Mingxin; Liu Zhiqiang; Song Fengrui; Liu Zhongying*; Investigation of plasma metabolomics and neurotransmitter dysfunctionin the process of Alzheimer's disease rat induced by amyloid beta 25-35, RSC Advances, 2019, 9(32): 18308-18319.
8. Wei Mengying; Liu Yuanyuan; Pi Zifeng; Li Shizhe; Hu Mingxin; He Yang; Yue Kexin; Liu Tianshu; Liu Zhiqiang; Song Fengrui; Liu Zhongying*; Systematically Characterize the Anti-Alzheimer’s Disease Mechanism of Lignans from S. chinensis Based on In-Vivo Ingredient Analysis and Target-Network Pharmacology Strategy by UHPLC–Q-TOF-MS, molecules, 2019, 24(7): 1203-1230.
9. 刘祥瑞，周天华，韦梦莹，李琪，周泉，谢珊珊：具有荧光性质的司美格鲁肽衍生物及其制备方法与应用，中国，ZL 2023 1 0185386.7（已授权）。
10. 关怡新，章逸鹏，韦梦莹，刘祥瑞：负载布地奈德的固体脂质纳米颗粒复合物及制备方法，中国，ZL20221 1558876.9（已授权）。
11. 刘忠英，刘媛媛，韦梦莹，马莹慧：一种甘草黄酮组分的提取及纯化方法，中国，CN108261438A。
2016.09-2019.07 吉林大学/中国科学院长春应用化学研究所联合培养 药物分析 博士
2013.09-2016.07 吉林大学/中国科学院长春应用化学研究所联合培养 药学 硕士
2009.09-2013.07 吉林大学农学（植物学）学士
2023.05-至今 浙江大学长三角智慧绿洲创新中心 未来健康实验室 特聘研究员
2024.10-至今 浙江大学药学院 兼聘研究员、硕士导师
2021.08-2023.05 浙江大学基础医学院 助理研究员、博士后
2019.09-2021.06 养生堂药业有限公司药品 研究员
科研项目
国家自然科学基金委青年基金，五味子木脂素组分抑制认知相关脑区中小胶质细胞M1型极化治疗阿尔茨海默病的药效物质及机制研究，负责人（2023-2025）
论文与专利
1. Yuying Wu#, Mengying Wei#, Mengyao Wang, Minsong Guo, Hengyuan Yu, Yong Chen, Tengfei Xu,Yuan Zhou*, Schisandra total lignans ameliorate neuronal ferroptosis in 3xTg-AD mice via regulating NADK/NADPH/GSH pathway. Phytomedicine, 2025, 140:156612.
2. Zhao Jiahui#; Wei Mengying#;Guo Minsong; Wang Mengyao; Niu Hongxia; Xu Tengfei; Zhou Yuan*; GSK3: A potential target and pending issues for treatment of Alzheimer's disease, CNS Neuroscience & Therapeutics, 2024, 30(7): e14818.
3. Wei Mengying; Liu Zhongying*; Liu Yuanyuan; Li Shizhe; Hu Mingxin; Yue Kexin; Liu Tianshu; He Yang; Pi Zifeng*; Liu Zhiqiang; Song Fengrui; Urinary and plasmatic metabolomics strategy to explore the holistic mechanism of lignans in S. chinensis in treating Alzheimer's disease using UPLC-Q-TOF-MS, Food & Function, 2019, 10(9): 5656-5668.
4. Hong Huang, Chuanming Fang, Hongxia Niu, Xiangjun Yin, Jiazhao Ruan, Mengying Wei*,
Yuan Zhou *; Effects of donepezil treatment on plasma and urine metabolites in amyloid beta-induced Alzheimer’s disease rats, Journal of Chromatography B, 2023, 1224: 123766.
5. Zhou Yuan（共一）; Wei Mengying（共一）; Fan Meiling; Liu Zhongying*; Wang Aimin; Liu Yuanyuan; Men Lihui; Pi Zifeng*; Liu Zhiqiang; Song Fengrui; Pharmacokinetic and metabolomics approach based on UHPLC-MS to evaluate therapeutic effect of lignans from S. Chinensis in alzheimer's disease, Journal of Chromatography B, 2021, 1178: 122859.
6. Wei Mengying; Ma Yinghui; Liu Yuanyuan; Zhou Yuan; Men Lihui; YueK exin; Pi Zifeng; Liu Zhiqiang; Liu Zhongying*; Urinary metabolomics study on the anti-inflammation effects of flavonoids obtained from Glycyrrhiza, Journal of Chromatography B, 2018, 1086(1086): 1-10.
7. Wei Mengying; Liu Yuanyuan; Pi Zifeng; Yue Kexin; Li Shizhe; Hu Mingxin; Liu Zhiqiang; Song Fengrui; Liu Zhongying*; Investigation of plasma metabolomics and neurotransmitter dysfunctionin the process of Alzheimer's disease rat induced by amyloid beta 25-35, RSC Advances, 2019, 9(32): 18308-18319.
8. Wei Mengying; Liu Yuanyuan; Pi Zifeng; Li Shizhe; Hu Mingxin; He Yang; Yue Kexin; Liu Tianshu; Liu Zhiqiang; Song Fengrui; Liu Zhongying*; Systematically Characterize the Anti-Alzheimer’s Disease Mechanism of Lignans from S. chinensis Based on In-Vivo Ingredient Analysis and Target-Network Pharmacology Strategy by UHPLC–Q-TOF-MS, molecules, 2019, 24(7): 1203-1230.
9. 刘祥瑞，周天华，韦梦莹，李琪，周泉，谢珊珊：具有荧光性质的司美格鲁肽衍生物及其制备方法与应用，中国，ZL 2023 1 0185386.7（已授权）。
10. 关怡新，章逸鹏，韦梦莹，刘祥瑞：负载布地奈德的固体脂质纳米颗粒复合物及制备方法，中国，ZL20221 1558876.9（已授权）。
11. 刘忠英，刘媛媛，韦梦莹，马莹慧：一种甘草黄酮组分的提取及纯化方法，中国，CN108261438A。
企业研发项目
1. 高生物利用度羟基红花黄色素A口服制剂的预开发，项目负责人（2024-2026）
2. 浙江大学长三角智慧绿洲-华润三九创新递送技术联合研究院子项目，项目负责人（2024-2026）
3. ZP036新型口服制剂研究开发，主要参与人（2021-2024）
4. 高口服生物利用度制剂开发，主要参与人（2021-2022）
5. 感冒新药项目研发，项目负责人（2019-2021）
6. 感染性溃疡（糖尿病足）新药研发项目，主要参与人（2019-2021）
7. 中药医院制剂开发前期调研，主要参与人（2019-2021）
研发产品：
1.Whiteasy 柏薇媞养发好睡丸：
2.Whiteasy 柏薇媞雪肌丸
